This study aims to develop green and sustainable advanced synthetic methods based
on redox cyclization. Elemental sulfur is shown to promote the efficient synthesis
of 2-substituted benzothiazoles from 2,2′-dinitrodiphenyl disulfides and benzylamines
via redox cyclization in the absence of transition-metal catalysts and solvents. The
2-substituted benzothiazoles are obtained in good to excellent yields. This synthetic
methodology is highly atom-economical and does not require any external oxidizing
and/or reducing agents.
Key words
redox cyclization - benzothiazoles - 2,2′-dinitrodiphenyl disulfides - benzylamines
- elemental sulfur - atom-economical
