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DOI: 10.1055/a-1610-9479
Effekt der Lufttamponade bei Patienten mit epiretinalen Membranen und intraretinalen zystoiden Veränderungen nach Vitrektomie mit Membrane Peeling – eine prospektive randomisierte Studie
Article in several languages: English | deutschZusammenfassung
Hintergrund Die Auswirkungen der Lufttamponade bei Patienten nach Vitrektomie mit Membrane Peeling aufgrund von epiretinalen Membranen (ERM) werden kontrovers diskutiert. Ziel der Studie ist es, Unterschiede in den Ergebnissen zwischen Lufttamponade und „balanced salt solution“ (BSS) in einer Patientengruppe mit präoperativen intraretinalen zystoiden Veränderungen zu untersuchen.
Patienten und Methoden Diese randomisierte prospektive Studie inkludierte Patienten mit ERM und intraretinalen zystoiden Veränderungen, die zur Pars-plana-Vitrektomie mit Membrane Peeling vorgesehen waren. Lufttamponade oder BSS am Ende der Operation wurde entsprechend der Randomisierung durchgeführt. Optische Kohärenztomografie und Bestimmung des bestkorrigierten Fernvisus (DCVA) erfolgten präoperativ, 5 Tage und 3 Monate nach der Operation.
Resultate Von 96 in die Studie rekrutierten Patienten hatten 85 ein vollständiges „follow-up“ und konnten in die Analysen der Ergebnisse eingeschlossen werden. Die mediane Verbesserung des DCVA war + 16 ETDRS-Buchstaben (IQR: 8 – 22) bei Patienten mit BSS und + 13 ETDRS-Buchstaben (IQR: 8 – 17) bei Patienten mit Lufttamponade. Es zeigte sich ein Trend für eine stärkere Verbesserung des DCVA bei BSS verglichen zur Lufttamponade, jedoch nicht statistisch signifikant.
Schlussfolgerung Es zeigten sich keine statistisch signifikanten Unterschiede in Bezug auf Resorption der präoperativen intraretinalen zystoiden Veränderungen, Verbesserung des DCVA und des postoperativen DCVA zwischen BSS und Lufttamponade.
Schlüsselwörter
Lufttamponade - epiretinale Membran - Vitrektomie mit Membrane Peeling - intraretinale zystoide VeränderungenPublication History
Received: 22 June 2021
Accepted: 20 August 2021
Article published online:
08 November 2021
© 2021. Thieme. All rights reserved.
Georg Thieme Verlag KG
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