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Klin Monbl Augenheilkd 2023; 240(10): 1192-1198
DOI: 10.1055/a-1610-9479
Klinische Studie

Effect of Air Tamponade among Patients with Epiretinal Membranes and Intraretinal Cystoid Changes Undergoing Vitrectomy with Membrane Peeling – A Prospective Randomized Trial

Article in several languages: English | deutsch
Christoph Leisser
1   Augenabteilung, Hanusch-Krankenhaus, Wien, Österreich
,
Manuel Ruiss
2   Vienna Institute for Research in Ocular Surgery, Hanusch-Krankenhaus, Wien, Österreich
,
Caroline Pilwachs
2   Vienna Institute for Research in Ocular Surgery, Hanusch-Krankenhaus, Wien, Österreich
,
Julius Hienert
1   Augenabteilung, Hanusch-Krankenhaus, Wien, Österreich
,
Kristina Stjepanek
1   Augenabteilung, Hanusch-Krankenhaus, Wien, Österreich
,
Oliver Findl
1   Augenabteilung, Hanusch-Krankenhaus, Wien, Österreich
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Abstract

Background The effect of air tamponade among patients undergoing vitrectomy with membrane peeling for removal of epiretinal membranes (ERM) is controversially discussed. The aim of the present study was to analyze differences in outcomes between air tamponade and balanced salt solution (BSS) in a study population with preoperative intraretinal cystoid changes.

Patients and Methods This randomized study included patients scheduled for pars plana vitrectomy with membrane peeling owing to ERM and intraretinal cystoid changes. Air tamponade or BSS at the end of surgery was applied according to preoperative randomization. Optical coherence tomography and best-corrected distance visual acuity (DCVA) measurements were performed before surgery, 5 days after surgery, and 3 months after surgery.

Results From 96 patients included, 85 eyes had full follow-up and could be included for analysis. Median improvement of DCVA was + 16 EDTRS letters (IQR: 8 to 22) among patients with BSS, while it was + 13 EDTRS letters (IQR: 8 to 17) among patients with air tamponade. There was a trend for better improvement of DCVA when BSS was left at the end of surgery, compared to air tamponade, but not reaching statistical significance.

Conclusions There were no statistically significant differences concerning resorption of preoperative intraretinal cystoid changes, improvement of visual acuity, and final DVCA between air tamponade and BSS.

Key words

air tamponade - epiretinal membranes - vitrectomy with membrane peeling - intraretinal cystoid changes


Publication History

Received: 22 June 2021

Accepted: 20 August 2021

Article published online:
08 November 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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