Carbon–Carbon Bond Formation Mediated by an Iron(0)–Olefin Pincer Complex

Zachary S. Lincoln; Melissa R. Hoffbauer; Vlad M. Iluc

doi:10.1055/a-2615-1768

Synthesis, Table of Contents

Synthesis 2025; 57(16): 2521-2529
DOI: 10.1055/a-2615-1768

paper

Romanian Chemists in Synthesis

Carbon–Carbon Bond Formation Mediated by an Iron(0)–Olefin Pincer Complex

Zachary S. Lincoln

,

Melissa R. Hoffbauer

,

Vlad M. Iluc ∗

Abstract

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Abstract

C–H functionalization is a highly appealing strategy for accessing complex molecular structures. Herein, we show that π-tethered pincer ligands can engage in C–H activation when coordinated to iron. These reactions result in C(sp²)–C(sp²) bond formation through oxidative coupling and β-hydride elimination/reductive elimination pathways with alkynes and isocyanides.

Key words

low-valent iron - coupling - alkenes - alkynes - isocyanides

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References

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