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Synthesis
DOI: 10.1055/a-2685-2029
Short Review

Design, Synthesis, and Self-Organization of Nature- and Bio-Inspired Homochiral Helical Complex Systems

Authors

  • Virgil Percec

    1   Chemistry, University of Pennsylvania, Philadelphia, United States (Ringgold ID: RIN6572)

  • Jasper Adamson

    1   Chemistry, University of Pennsylvania, Philadelphia, United States (Ringgold ID: RIN6572)
    2   School of Engineering, Tallinn University of Technology, Tallinn, Estonia (Ringgold ID: RIN54561)

  • Dipankar Sahoo

    1   Chemistry, University of Pennsylvania, Philadelphia, United States (Ringgold ID: RIN6572)

  • Devendra S. Maurya 

    1   Chemistry, University of Pennsylvania, Philadelphia, United States (Ringgold ID: RIN6572)

Gefördert durch: National Science Foundation DMR-2104554 and DMR-1720530
Gefördert durch: European Union Agency for Cybersecurity Grant no. 2021-2027.6.01.23-0034
Gefördert durch: Alexander von Humboldt Foundation, Germany
Gefördert durch: P. Roy Vagelos chair at the University of Pennsylvania
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Helical homochirality is available in Nature, Biology and, most recently, also in synthetic systems. Selected examples of helical complex systems from Nature, Biology and synthetic chemistry will be briefly discussed, most probably for the first time, in a single publication. When available, the mechanisms of the origin of their homochirality will be presented. In order to encourage new discoveries, the historical events of many discoveries will also be highlighted. Potential connections between the homochirality in nature and biology as well as in nature- and bio-inspired macroscopic, molecular and supramolecular complex systems will be mentioned.



Publikationsverlauf

Eingereicht: 05. Juli 2025

Angenommen nach Revision: 18. August 2025

Accepted Manuscript online:
18. August 2025

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