PDF herunterladen
Synthesis
DOI: 10.1055/a-2705-2270
Paper

Synthetic Studies on Lolium Alkaloids

Authors

  • Daniel Zuschlag

    1   Department of Chemistry, University of Pennsylvania, Philadelphia, United States (Ringgold ID: RIN6572)

  • Mesut Cakmak

    2   Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany

  • Chrstian Kuttruff

    2   Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany

  • Peter Mayer

    3   Department of Chemistry, Ludwig-Maximilians-Universität, München, Germany

  • Dirk Trauner 

    1   Department of Chemistry, University of Pennsylvania, Philadelphia, United States (Ringgold ID: RIN6572)

Gefördert durch: BioXFEL Science and Technology Center CHE-1900154
Weitere Informationen
 als PDF herunterladen Alle Artikel dieser Rubrik
Preview

We report the first total synthesis of several natural products of the loline family, including the unusual chloropyrrolizidine alkaloid lolidine. We demonstrate the utility of an azide intermediate in our synthesis towards click-chemistry and late-stage functionalization. Lastly, we further explore the CO2 absorbing properties of temuline, as well as a potential application of loline as a chiral ligand in palladium chemistry.



Publikationsverlauf

Eingereicht: 31. August 2025

Angenommen nach Revision: 18. September 2025

Accepted Manuscript online:
18. September 2025

© . Thieme. All rights reserved.

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany