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Synthesis
DOI: 10.1055/a-2705-4396
DOI: 10.1055/a-2705-4396
Paper
Published as part of the Special Issue in Honor of Prof. Franziska Schoenebeck, the
2025 Women in Chemistry Award Winner
Synthesis and Evaluation of Hydrogen-Bonding Organocatalysts Bearing P(V)-Stereogenic Centers
Authors
Supported by: China Scholarship Council and FAZIT-STIFTUNG
Abstract
In this study, we report the synthesis of a novel series of chiral hybrid scaffolds, each featuring a P(V)-stereogenic center integrated with a chiral backbone via squaramide or thiourea linkers. The catalytic performance of these newly developed organocatalysts was evaluated in asymmetric transfer hydrogenation reactions, showing moderate activity and limited selectivity.
Publication History
Received: 30 June 2025
Accepted after revision: 14 September 2025
Article published online:
09 October 2025
© 2025. Thieme. All rights reserved.
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
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