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Syntheses of Cassiarins A and B
Y.-S. Yao, Z.-J. Yao*
Shanghai Institute of Organic Chemistry and University of Science and Technology of China, Hefei, P. R. of China
22 January 2009 (online)
Cassiarins A and B are isolated form Cassia siamea which has been used as traditional medicine for the treatment of malaria. Both cassiarins A and B show potent antiplasmodial activity against Plasmodium falciparum with an IC50 of 0.005 and 6.9 mg/mL, respectively.