Synfacts 2009(2): 0190-0190  
DOI: 10.1055/s-0028-1087655
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Efficient Ni(II)-Catalyzed Dialkylation of Aromatic Aldehydes

Contributor(s): Paul Knochel, Andreas J. Wagner
Y. Fu, J.-X. Wang*, K. Wang, Y. Hu
Northwest Normal Universtity, Lanzhou and Lanzhou University, P. R. of China
Further Information

Publication History

Publication Date:
22 January 2009 (online)


Functionalized organozinc halides can be reacted with aromatic electron-rich aldehydes in the presence of a silylating agent and catalytic amounts of Ni(acac)2. The resulting dialkylation products are obtained in good to excellent yields. The reaction proceeds under mild conditions.