A Novel Synthesis of N-But-3-enyl-α- and β-Amino
Acids

T. T. Van Nguyen; Robert T. C. Brownlee; Andrew B. Hughes

doi:10.1055/s-0028-1088072

PAPER

A Novel Synthesis of N-But-3-enyl-α- and β-Amino Acids

T. T. Van Nguyen, Robert T. C. Brownlee, Andrew B. Hughes*
Department of Chemistry, La Trobe University, Victoria 3086, Australia
Fax: +61(3)94791399; e-Mail: a.hughes@latrobe.edu.au;

Abstract

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Abstract

N-But-3-enyl-α- and β-amino acids can be prepared by cleaving 1,3-oxazolidin-5-ones and 1,3-oxazinan-6-ones in the presence of allylsilanes and boron trifluoride etherate at room temperature in good to excellent yields.

Key words

1,3-oxazolidin-5-ones - 1,3-oxazinan-6-ones - amino acids - allylations - Lewis acids

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References

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