STUDY OF THE CYTOSTATIC ACTIVITY OF IGUESTERIN AND RELATED COMPOUNDS

A. G. Gonzalez; V. Darias; J. Boada; G. Alonso

doi:10.1055/s-0028-1097602

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Planta Med 1977; 32(7): 282-286
DOI: 10.1055/s-0028-1097602

STUDY OF THE CYTOSTATIC ACTIVITY OF IGUESTERIN AND RELATED COMPOUNDS

A. G. Gonzalez, V. Darias, J. Boada, G. Alonso

Instituta de Productos Naturales Orgánicos del CSIC – La Laguna – Tenerife – Canary Islands. Instituto de Quítnica Médica CSIC – Madrid – Spain.

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Publication Date:
13 January 2009 (online)

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Abstract

The powerful cytostatic activity of iguesterin, a new hydroxymethylenequinonoid di-nor-triterpene, isolated from Maytenus canariensis for the first time in this laboratory, was demonstrated. At the same time related compounds were studied in the hope that some connection between structure and activity could be suggested, as well as the mechanism of this cytostatic action.