Reduction of Acetophenones Using
Borohydride Exchange Resins (BER) and a BER-Lithium Salt System

Jane Luiza Nogueira Fernandes; Marcos Costa de Souza; Eugênia Cristina Souza Brenelli; José Afrânio Brenelli

doi:10.1055/s-0029-1217040

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Synthesis 2009(23): 4058-4062
DOI: 10.1055/s-0029-1217040

PAPER

Reduction of Acetophenones Using Borohydride Exchange Resins (BER) and a BER-Lithium Salt System

Jane Luiza Nogueira Fernandes, Marcos Costa de Souza*, Eugênia Cristina Souza Brenelli*^†, José Afrânio Brenelli
Universidade Federal Fluminense, Campus Valonguinho, Instituto de Química, Departamento de Química Orgânica, Outeiro de São João Batista s/n, Centro, Niterói-RJ, CEP 24020-150, Brazil
Fax: +55(21)26292230; e-Mail: gqomarc@vm.uff.br;

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Publication History

Received 15 July 2009
Publication Date:
12 October 2009 (online)

Abstract
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Abstract

Borohydride reduction of acetophenones was carried out with the borohydride-form of an anion exchange polystyrene-divinylbenzene resin. High yields were achieved and reaction rates were significantly increased by the addition of LiNO₃, LiCl, LiBr or LiI without decreasing yield.

Key words

reductions - polymers - ketones - exchange resin - lithium salts

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