Synfacts 2010(1): 0001-0001  
DOI: 10.1055/s-0029-1218392
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of (+)-Haplophytine

Contributor(s): Philip Kocienski
K. C. Nicolaou*, S. M. Dalby, S. Li, T. Suzuki, D. Y.-K. Chen*
Institute of Chemical and Engineering Sciences, A*STAR, Singapore; The Scripps Research Institute, La Jolla and University of California, San Diego, USA
Further Information

Publication History

Publication Date:
21 December 2009 (online)

Significance

The first of the five quaternary centers in haplophytine was installed by an oxidative coupling reaction (A + BC) mediated by phenyliodonium bis(trifluoroacetate) (PIFA).