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Synthesis 2011(3): 431-436  
DOI: 10.1055/s-0030-1258372
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

The Furan Approach to Oxacycles: New Entry to the Synthesis of Isodideoxynucleosides

Pilar Canoa, Zoila Gándara, Manuel Pérez, Rafael Gago, Generosa Gómez*, Yagamare Fall*
Departamento de Química Orgánica, Facultade de Química, Universidade de Vigo, 36310 Vigo, Spain
Fax: +34(986)812262; e-Mail: yagamare@uvigo.es; e-Mail: ggomez@uvigo.es;
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Publication History

Received 12 August 2010
Publication Date:
05 January 2011 (online)

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Abstract

We describe a stereoselective synthesis of isonucleosides of cis and trans configuration using the furan approach, hence enlarging the scope of our methodology.

Key words

singlet oxygen - stereoselective synthesis - nucleosides - isonucleosides - Mitsunobu reaction

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