Synthesis of Biaryl Derivatives
by Using Ruthenium-Mediated [2+2+2] Cyclotrimerization
and Suzuki-Miyaura Cross-Coupling as Key Steps

Sambasivarao Kotha; Vittal Seema; Shaikh M. Mobin

doi:10.1055/s-0030-1260009

PAPER

Synthesis of Biaryl Derivatives by Using Ruthenium-Mediated [2+2+2] Cyclotrimerization and Suzuki-Miyaura Cross-Coupling as Key Steps

Sambasivarao Kotha*, Vittal Seema, Shaikh M. Mobin
Department of Chemistry, Indian Institute of Technology-Bombay, Powai, Mumbai 400 076, India
Fax: +91(22)25723480; e-Mail: srk@chem.iitb.ac.in;

Abstract

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Abstract

Functionalized biaryl derivatives have been prepared by applying [2+2+2] cyclotrimerization with the aid of Grubbs’ first-generation catalyst (G-I). The trimerized products were subjected to the Suzuki-Miyaura cross-coupling reaction sequence to generate highly functionalized biaryl derivatives.

Key words

terphenyl - quinquephenyl - [2+2+2] cyclotrimerization - Suzuki-Miyaura cross-coupling - metathesis

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CCDC-797048 (7b) contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data_request/cif.

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