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Synthesis 2011(20): 3359-3363  
DOI: 10.1055/s-0030-1260185
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Wittig Olefination of Trifluoromethyl Ketones and Allylic Carbonates Mediated by Phosphines

Tong Wang, Li-Tao Shen, Song Ye*
Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. of China
Fax: +86(10)62554449; e-Mail: songye@iccas.ac.cn;
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Publication History

Received 20 June 2011
Publication Date:
24 August 2011 (online)

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Abstract

The Wittig olefination of trifluromethyl ketones and allylic carbonates mediated by tributylphosphine was realized to give corresponding trifluoromethyl dienes in good yields with excellent E-selectivities.

Key words

Wittig - trifluoromethyl ketones - trifluoromethyl olefins - ylides - allylic carbonate

    Primary data for this article are available online and can be cited using the following DOI: 10.4125/pd0015th:
  • Primary Data

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