Synfacts 2011(8): 0876-0876  
DOI: 10.1055/s-0030-1260734
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Ruthenium-Catalyzed Regio- and Enantio-selective Allylic Substitution with Water

Contributor(s): Mark Lautens, Patrick T. Franke
N. Kanbayashi, K. Onitsuka*
Osaka University, Japan
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Publikationsverlauf

Publikationsdatum:
20. Juli 2011 (online)

Significance

A highly efficient regio- and enantio-selective allylic substitution of monosubstituted allylic chlorides with water has been developed. The products are obtained in excellent enantio­selectivities up to 97%.