Synfacts 2011(8): 0856-0856  
DOI: 10.1055/s-0030-1260816
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Asymmetric Hydrogenation of Heterocyclic Compounds

Contributor(s): Hisashi Yamamoto, Zhi Li
R. Kuwano*, N. Kameyama, R. Ikeda
Kyushu University, Fukuoka, Japan
Further Information

Publication History

Publication Date:
20 July 2011 (online)


This report describes a highly enantioselective hydrogenation of various five-membered heterocyclic compounds containing two heteroatoms. The catalyst is generated from Ru(η³-methallyl)2(cod) and a trans-chelating bisphosphine ligand.