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Planta Med 2011; 77(11): 1189-1202
DOI: 10.1055/s-0030-1271187
Lectures GA Conference
Reviews
© Georg Thieme Verlag KG Stuttgart · New York

A Quarter Century of Pharmacognostic Research on Panamanian Flora: A Review[*]

Catherina Caballero-George1 , Mahabir P. Gupta2
  • 1Institute of Scientific Research and High Technology Services (INDICASAT‐AIP), Panama, Republic of Panama
  • 2Center for Pharmacognostic Research on Panamanian Flora (CIFLORPAN), College of Pharmacy, University of Panama, Panama, Republic of Panama
Further Information

Publication History

received March 25, 2011 revised May 5, 2011

accepted May 10, 2011

Publication Date:
14 June 2011 (online)

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Abstract

Panama is a unique terrestrial bridge of extreme biological importance. It is one of the “hot spots” and occupies the fourth place among the 25 most plant-rich countries in the world, with 13.4 % endemic species. Panamanian plants have been screened for a wide range of biological activities: as cytotoxic, brine shrimp-toxic, antiplasmodial, antimicrobial, antiviral, antioxidant, immunosuppressive, and antihypertensive agents. This review concentrates on ethnopharmacological uses of medicinal plants employed by three Amerindian groups of Panama and on selected plants with novel structures and/or interesting bioactive compounds. During the last quarter century, a total of approximately 390 compounds from 86 plants have been isolated, of which 160 are new to the literature. Most of the work reported here has been the result of many international collaborative efforts with scientists worldwide. From the results presented, it is immediately obvious that the Panamanian flora is still an untapped source of new bioactive compounds.

Key words

bioassays - Panamanian plants - ethnomedicine - novel compounds

Supporting Information

1 Invited review – Planta Medica special supplement; editor, Prof. Dr. H. Kolodziej.

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1 Invited review – Planta Medica special supplement; editor, Prof. Dr. H. Kolodziej.

Prof. Dr. Mahabir P. Gupta

Center for Pharmacognostic Research on Panamanian Flora (CIFLORPAN)
College of Pharmacy

Box 0824-00172

Panama

Republic of Panama

Phone: +507 5 23 63 11

Fax: +507 2 64 07 89

Email: mahabirpgupta@gmail.com

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