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DOI: 10.1055/s-0031-1273526
Multilab Reproduction on Component Quantification and Qualitative Identification of Blueberry Leaf Extracts via NMR
Vaccinium spp. (Blueberries, Cranberries, and Bilberries) have been traditionally used by indigenous cultures and are linked to maintenance and low instances of diabetes onset [1]. The ability to quickly screen extracts for novel compounds, new sources or higher levels of known compounds, monitoring of „ripeness“, and source would greatly optimize the selection of natural product sources for possible efficacy. Similarly, the ability to screen extracts at multiple locations allows analysis on a global scale. NMR's high reproducibility imparts cross platform quantification of individual compounds and qualitative assessment (chemometric modeling), which makes it possible to compare data at different sites. Here we present the results on a multi-site reproducibility study to identify and quantify compounds directly from the spectrum of the raw leaf extract and qualitatively identify the source from data acquired at different locations by a proton (1H) experiment which takes less than 10 minutes.
References: [1] Leduc C, et al. (2006), J. Ethnoparmacology, 105: 55–63.