Planta Med 2011; 77(18): 2037-2041
DOI: 10.1055/s-0031-1280064
Natural Product Chemistry
Original Papers
© Georg Thieme Verlag KG Stuttgart · New York

Biphenyl and Biphenyl Ether Quinolizidine N-oxide Alkaloids from Lagerstroemia indica L.

IkSoo Lee1 , 2 , UiJoung Youn3 , HongJin Kim1 , ByungSun Min4 , Jin Sook Kim2 , KiHwan Bae1
  • 1College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea
  • 2Diabetic Complications Research Center, Division of Traditional Korean Medicine Integrated Research, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea
  • 3College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea
  • 4College of Pharmacy, Catholic University of Daegu, Gyeongbuk, Republic of Korea
Further Information

Publication History

received January 27, 2011 revised May 30, 2011

accepted June 13, 2011

Publication Date:
27 July 2011 (online)


Four new biphenyl and biphenyl ether quinolizidine N-oxide alkaloids, 5-epi-dihydrolyfoline N-oxide (1), decamine N-oxide (2), lagerstroemine N-oxide (3), and lagerine N-oxide (4), were isolated from the aerial parts of Lagerstroemia indica, and their structures were established by extensive spectroscopic studies. In addition, the inhibitory effects of isolated compounds on rat lens aldose reductase (RLAR) were examined.

Supporting Information


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Prof. Dr. KiHwan Bae

College of Pharmacy
Chungnam National University

Daejeon 305-764

Republic of Korea

Phone: +82 42 8 21 59 25

Fax: +82 42 8 23 65 66