Stereoselective Rhodium-Catalyzed Amination of Alkenes

Significance

The current work describes a ­rhodium-catalyzed intermolecular aziridination and C-H amination of alkenes to produce chiral carbamate-protected aziridines and allylic amines. The products can be isolated in good yields and diastereoselectivities employing a readily available chiral N-tosyloxycarbamate. The general reaction scale for this transformation is 0.25 mmol.