DOI: 10.1055/s-00000131

Synfacts

Issue 12 · Volume 2011 · December 2011 DOI: 10.1055/s-002-22456

Synform

A109
SYNFORM ISSUE 2011/12

Synthesis of Natural Products and Potential Drugs

z1265
All PDFs of this category
1265
Synthesis of (+)-Ophiobolin A
1266
Synthesis of MK-3281
1267
Synthesis of PF-03463275
1268
Synthesis of (+)-Gliocladin C
1269
Synthesis of Fesoterodine
1270
Synthesis of the Bismurrayaquinone A
1271
Synthesis of (-)-Maoecrystal Z
1272
Synthesis of (-)-Hodgkinsine B
1273
Synthesis of BIRT2584
1274
Synthesis of Crizotinib (PF-02341066)
1275
Synthesis of PF-04191834
1276
Synthesis of MK-8245
1277
Synthesis of a Renin Inhibitor
1278
Synthesis of (+)-Grandisine D
1279
Synthesis of a TRPV1 Antagonist
1280
Synthesis of TAK-475
1281
Synthesis of (-)-N-Methylwelwitindolinone C Isothiocyanate

Synthesis of Heterocycles

z1283
All PDFs of this category
1283
Pd-Catalyzed Synthesis of Phenanthridinones by Double C-H Activation
1284
Palladium-Catalyzed Enantioselective Synthesis of Silacyles
1285
Ethers via Catalytic Asymmetric Thiofunctionalization of Alkenyl Alcohols
1286
Synthesis of Pyrimidines via N-Vinyl Tertiary Enamides
1287
Pd-Catalyzed Enantioselective Synthesis of 2-Methyl Indolines
1288
Metal-Free Synthesis of 2-Trifluoromethyl Furans
1289
Synthesis of Chromones from 2,3-Allenoic Acids and Benzynes
1290
Iron-Catalyzed Synthesis of Aminoindolizines and Quinolines
1291
Metal-Free Synthesis of Pyrroles From Morita-Baylis-Hillman Acetates
1292
Copper-Catalyzed One-Pot Synthesis of 5-Sulfonamidopyrazoles
1293
Two-Step Heck-Mediated Synthesis of Pyrroles from Sulfonamides and Bromoacetylenes
1294
Cycloaddition Approach to Substituted Thiophenes
1295
Heteroannulation Route to Benzothiophenes from 2-Bromo Alkynylbenzenes
1296
A Multicatalytic Domino Heteroannulation Approach to Dihydroquinolines
1297
Pd-Catalyzed C-H Activation Route to Dibenzophosphole Oxides

Synthesis of Materials and Unnatural Products

z1299
All PDFs of this category
1299
Nickel-Catalyzed Synthesis of Strained Phenacenes
1300
One Step to Polyenes
1301
An All-Organic Porphyrin and its Properties
1302
Polymerization of Diisocyanobenzenes Bearing Alkoxy Side Chains
1303
A One-Pot Approach to ‘Shutting the Lights Off’ in the Presence of Mercury Ion
1304
Delocalized Radicals
1305
Synthesis of a New exo-Heterocyclic Diene
1306
High-Yielding One-Pot Synthesis of Oxazine Photochromes
1307
Anion-Templated Yin Yang: Janus [2]Rotaxanes
1308
Putting a B in Polymer
1309
The Smaller the Redder
1310
A One-Pot Route to 3-Vinyl Coumarins
1311
Route to Functionalized Sumanenes

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z1313
All PDFs of this category
1313
Asymmetric α-Allylation of Aldehydes with Simple Allylic Alcohols
1314
Copper-Catalyzed Asymmetric α-Arylation of N-Acyloxazolidinones
1315
Cu-Catalyzed Asymmetric α-Arylation of Carbonyls
1316
Palladium-Catalyzed Enantioselective Fluorination of Allylic Halides
1317
Enantioselective Fluorination of Epoxides via Cooperative Catalysis
1318
Enantioselective Rhodium-Catalyzed Conjugate Addition
1319
A Simplified Catalytic System for Direct Asymmetric Aldol Reaction of Thioamides
1320
Hydroamination of Dienes by Gold(I)/Menthol Cooperative Catalysis
1321
Silver-Catalyzed Enantioselective [3+2] Cycloadditions
1322
Helical Macromolecular Ligand for Asymmetric Suzuki Coupling
1323
Pd-Catalyzed Asymmetric Allylic Amination
1324
Palladium-Catalyzed Enantioselective α-Arylation
1325
Readily Accessible Diene Ligands for Enantioselective Conjugate Additions
1326
Enantioselective Intramolecular Benzylic C-H Bond Amination
1327
Asymmetric Epoxidation Catalyzed by Titanium(salalen) Complex
1328
Titanium-Catalyzed Enantioselective Oxidation of Aryl Sulfides
1329
Diastereo- and Enantioselective Direct Aldol Reactions Mediated by CoCl2/l-Proline
1330
Niobium-Catalyzed Asymmetric Aldol-Type Reactions
1331
Rh-Catalyzed Enantioselective Addition of Arylboronic Acids to Enones
1332
Cu-Catalyzed Asymmetric Tandem Dual Michael Reaction of Dialkylzinc to Enones
1333
Cu(I)/BINAP-Catalyzed Synthesis of Pyro-glutamates
1334
Copper-Catalyzed Asymmetric Henry Reaction
1335
Stereoselective Rhodium-Catalyzed Amination of Alkenes
1336
Catalyst-Controlled Diastereo- and Enantioselective Hydrogenation
1337
Manganese-Catalyzed Enantioselective cis-Dihydroxylation
1338
Copper-Catalyzed Tandem 1,4-Addition-Fluorination Sequence
1339
Pd-Catalyzed Intramolecular Asymmetric Allylic Amination
1340
Ir(I)-Catalyzed C-H Bond Activation of 2-(Alkylamino)pyridines with Alkenes
1341
Synthesis of Optically Pure Bulky Carbinols via Kinetic Resolution
1342
Stereocontrol of the Combined C-H Functionalization/Cope Rearrangement

Metal-Mediated Synthesis

z1343
All PDFs of this category
1343
Catalytic Enantioselective γ-Alkylation of Carbonyl Compounds
1344
Synthesis of Trifluoroethyl-Substituted Ketones
1345
Takai-Analogous One-Step Preparation of (E)-Vinylsilanes
1346
Direct Conversion of Carboxylic Acids into Ketones
1347
Bridgehead Radicals for Coupling of Oxygenated Carbocycles
1348
Copper-Catalyzed Intramolecular Oxidative Cyclization
1349
An Organocatalyzed Michael Addition-Cyclization Sequence to Spirolactones
1350
One-Pot Synthesis of 2,4-Dienols from Cycloalkenones
1351
Improved Conversion of Aryl and Vinyl Triflates into Bromides and Chlorides
1352
Cu-Mediated Cyanation of Aryl Halides
1353
Ti-Mediated Tandem Ethylation and Functionalization of Allylic Alcohols
1354
New Insights into Anion Relay Chemistry
1355
Difluoromethylation of Carbonyls and Imines with TMSCF2H
1356
Mukaiyama Cross-Aldol Reaction to Yield anti-β-Siloxy-α-haloaldehydes
1357
Nickel-Catalyzed Formation of Cyclo-pentenones via Cycloaddition

Organo- and Biocatalysis

z1359
All PDFs of this category
1359
Friedel-Crafts Alkylation, Internal Redox Reaction, and Umpolung Cascade
1360
Asymmetric Reduction of Unprotected Indoles
1361
Enantiopure RNA Precursors from Nearly Racemic Starting Materials
1362
Morpholine-Catalyzed C3 Alkenylation of Indoles with Enals
1363
Phosphine-Catalyzed Heine Reaction
1364
Asymmetric Reduction of Ketones
1365
Dual-Catalytic Asymmetric Reactions
1366
Organocatalytic Pictet-Spengler Reaction in Natural Product Synthesis
1367
Organo-Click Synthesis of 1,2,3-Triazoles from Unactivated Ketones
1368
Phosphoric Acid Catalyzed Enantioselective Friedländer Condensations
1369
Synthesis of Piperidines through Intramolecular Aza-Michael Addition
1370
Catalytic Cycloetherification Using Bifunctional Thiourea Catalysts

Polymer-Supported Synthesis

z1371
All PDFs of this category
1371
Reduction of Nitroarenes with N2H4˙H2O Using Fe-Phen/C
1372
Oxidative Amidation of Alcohols with Amines Catalyzed by Au/DNA
1373
Suzuki-Miyaura Reaction with NHC-Cu-Pd MOF Catalysts
1374
Pd/C-Catalyzed Hiyama Cross-Coupling
1375
Solid-Supported Prolinol Ether Catalysts
1376
Ullmann Reaction of Aryl Iodides with Au@PMO
1377
Suzuki-Miyaura Coupling in Water with Pd@SBA-15©
1378
Oxidation with SiO2-Supported Iodoarene-RuCl3 Bifunctional Catalysts
1379
Microwave-Assisted Thionation of Amides Using a Solid-Supported P2S5
1380
A Poly(Imidazole-Palladium) Catalyst for Allylic Arylation/Alkenylation
1381
CuO on Alumina for C-O Coupling of Halides with Alcohols
1382
Disulfide Bond Formation with Polymer-Supported Reagent
1383
Suzuki Coupling of Alkynyl Bromides with Boronic Acids by Pd-SiO2@Fe3O4
1384
C-N and C-S Bond-Forming Cross-Coupling in Water with PS-PEG-Pd

Addenda and Errata

1385
Trienamines in Organocatalysis
1385
exo-Selective Diels-Alder Reaction of 2,4-Dienals and Nitroalkenes