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Synthesis 2013; 45(5): 625-632
DOI: 10.1055/s-0032-1318113
DOI: 10.1055/s-0032-1318113
paper
Synthesis of (–)-Muricatacin from Tri-O-acetyl-d-glucal
Further Information
Publication History
Received: 19 October 2012
Accepted after revision: 28 December 2012
Publication Date:
05 February 2013 (online)
Abstract
The total synthesis of (–)-muricatacin is achieved using commercially available tri-O-acetyl-d-glucal as the starting material. The structure of the intermediate chiral butenolide is established unambiguously by X-ray crystallographic analysis, which consequently leads to correction of a previous structural misassignment.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information
-
References
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For recent syntheses of muricatacin, see:
For a recent review on the synthesis of muricatacin and related compounds, see: