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Synthesis 2013; 45(6): 810-816
DOI: 10.1055/s-0032-1318147
DOI: 10.1055/s-0032-1318147
paper
Merging Cross-Metathesis and Radical Cyclization: A Straightforward Access to 4-Substituted Benzosultams
Autoren
Weitere Informationen
Publikationsverlauf
Received: 17. Dezember 2012
Accepted after revision: 11. Januar 2013
Publikationsdatum:
08. Februar 2013 (online)
Abstract
N-Alkyl-N-allyl-2-bromobenzenesulfonamides were functionalized by selective E-cross-metathesis with various alkenes. Subsequent radical cyclization initiated by 2,2′-azobis(isobutyronitrile) and tris(trimethylsilyl)silane gave the corresponding 4-substituted benzosultams directly in moderate-to-good yields.
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