Phytochemical and biological analysis of Mallotus oppositifolius (Euphorbiaceae)

FA Kabran; A Maciuk; TA Okpekon; K Leblanc; B Seon-Meniel; C Bories; P Champy; LA Djakouré; B Figadère

doi:10.1055/s-0032-1321134

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Planta Med 2012; 78 - PI447
DOI: 10.1055/s-0032-1321134

Phytochemical and biological analysis of Mallotus oppositifolius (Euphorbiaceae)

FA Kabran ¹^,², A Maciuk ¹, TA Okpekon ², K Leblanc ¹, B Seon-Meniel ¹, C Bories ¹, P Champy ¹, LA Djakouré ², B Figadère ¹

¹UMR 8076 CNRS, Faculty of Pharmacy, University Paris-Sud, France
²Laboratoire de Chimie Organique Biologique, UFR Sciences des Structures de la Matière et de Technologie, Abidjan, Côte d'Ivoire

Kongressbeitrag

Mallotus oppositifolius (Geiseler) Müll. Arg., (Euphorbiaceae), is an endemic shrub from tropical Africa forests and savannas. It is widely used in popular medicine against infections, intestinal worms an malaria. Extracts of different parts of the plant have been shown to have anti-inflammatory, antioxidant, antidiarrheic, antibacterial, antifungal and antitrypanosomal properties. The present work reports the isolation of 32 compounds from the leaves, stem barks and roots. Among these compounds, six phenolic compounds are newly described. Biological assessment of these isolated compounds on Trypanosoma brucei and Leishmania donovani are described.