A rapid extraction technique for dry plant materials utilizing flash chromatography with integrated multi-detection

Isolating single components for study from plant materials is challenging and often involves multiple steps using one or a combination of extraction techniques. Plants in their raw form may not solubilize easily in organic solvents and may require harsher extraction techniques incorporating pH changes or an application of heat to process. These techniques can pose risk of decomposition and be time-consuming. This work investigates the use of flash chromatography, frequently utilized to purify dry and liquid extracts or simplify complex botanical mixtures, to increase productivity of botanical isolations using on-line extraction and fractionation of pulverized dry plant materials. Goals of the study include decreasing extraction steps, solvent usage, and processing time.