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Planta Med 2013; 79(01): 87-91
DOI: 10.1055/s-0032-1327951
Natural Product Chemistry
Letters
Georg Thieme Verlag KG Stuttgart · New York

Chemical Constituents from the Fungus Amauroderma amoiensis and Their In Vitro Acetylcholinesterase Inhibitory Activities

Shuang Shuang Zhang
1   Food Science and Technology College, Nanjing Agricultural University, Nanjing, China
2   Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, China
,
Qing Yun Ma
2   Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, China
,
Xi Sheng Zou
3   State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China
,
Hao Fu Dai
2   Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, China
,
Sheng Zhuo Huang
2   Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, China
,
Ying Luo
2   Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, China
,
Zhi Fang Yu
1   Food Science and Technology College, Nanjing Agricultural University, Nanjing, China
,
Huai Rong Luo
3   State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China
,
You Xing Zhao
2   Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, China
› Author Affiliations
Further Information

Publication History

received 12 September 2012
revised 14 October 2012

accepted 21 October 2012

Publication Date:
23 November 2012 (online)

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Abstract

One new compound named amauroamoienin (1), together with thirteen known compounds (2–14), was isolated from the EtOAc extract of Amauroderma amoiensis. The structures of these compounds were elucidated by the analysis of 1D and 2D spectroscopic data and the MS technique. The bioassays of inhibitory activities of these isolates against acetylcholinesterase were evaluated, and compounds 1, 3, and 5 exhibited acetylcholinesterase inhibitory activities.

Key words

Amauroderma amoiensis - Ganodermataceae - amauroamoienin - acetylcholinesterase inhibitory activity

Supporting Information

 

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