Planta Med 2013; 79 - P85
DOI: 10.1055/s-0033-1336527

Antimicrobial Activity of the Seed Kernel and Leaf Extracts of Mangifera indica L. (Fam. Anacardiaceae) Against Escherichia coli

ADC Abergas 1, MCQ Aleria 1, ZJS Alimagno 1, KNC Batac 1, AFM De Lara 1, ECQ Dela Cruz 1, GLT Dela Torre 1, LSC Disu 1, LJC Flores 1, JP Jimenez 1, ML Lee 1, PMF Ocsan 1, RE Reyes 1, JP Sijas 1, TCP So 1, JJN Taguibao 1, KAG Tan 1, HT Uy 1, DM Uy Cana 1, MKMC Yap 1
  • 1University of the Philippines- Manila, College of Pharmacy, Taft Avenue corner Pedro Gil St., 1000 Manila, Philippines

Mango [Mangifera indica L. (Fam. Anacardiaceae)], particularly the carabao mango, is widely endemic in the Philippines and its seed kernels and mature leaves have many purported folkloric uses and pharmacologic activities that function as antioxidant, antitussive, antiviral, among others which were linked to its primary constituent, mangiferin, a xanthone glycoside. However, there are a limited number of studies on the antimicrobial activity of the aforementioned variety of mango. Hence, this study was carried out to qualitatively determine their chemical constituents and their possible antimicrobial activity. The general procedure performed was of two distinct sets: the (i) characterization of the crude extract, and (ii) the bioassay-guided fractionation. Results showed that the hexane fraction of the seed kernel possessed antimicrobial activity which was inferred to be due to the aglycone unit of mangiferin. It is recommended that spectroscopic tests (i.e. UV, IR, NMR, etc.) be conducted for further isolation and characterization. References: [1] He Q, Masibo M (2008) Comp Rev in Food Sci and Food Safety, 7(4): 309 – 319. [2] Shah KA, Patel MB, et al. (2010) Pharmacognosy Rev, 4(7): 42 – 48. [3] Jiagang D (2009) Study on mango leaf and mangiferin, < on Mango Leaf and Mangiferin.pdf>. [4] Quisumbing E (1978) Medicinal Plants of the Philippines, Katha Publishing Co., Quezon City, Philippines, 538 – 541.