Base-Mediated Synthesis of 1-Aryl-4-(phenylsulfonyl)butan-1-ones from 1,2-Bis(phenylsulfonyl)ethane and Ketones

Abstract

A new, simple, base-mediated addition reaction of 1,2-bis(phenylsulfonyl)ethane to ketones has been developed for the synthesis of 1-aryl-4-(phenylsulfonyl)butan-1-ones. This method represents the first example of preparing sulfones using 1,2-bis(phenylsulfonyl)ethane as the sulfone resource.

Key words

base - addition - 1,2-bis(phenylsulfonyl)ethane - ketones - sulfones

• Reference

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