Synthesis of Pyrrolo[3,2-b]carbazole Derivatives via Palladium-Catalyzed C–H Activation

Abstract

A simple method for the synthesis of different pyrrolo[3,2-b]carbazole derivatives by the reaction of 3-(acetylamino)carbazoles with various symmetrical diaryl-substituted alkynes via palladium-catalyzed C–H activation is reported.

Key words

3-aminocarbazoles - palladium catalysis - pyrrolo[3,2-b]carbazoles - C–H activation - diarylacetylenes

• References

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• 11 The crystal data for compounds 3a, 3e and 3i have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication nos. CCDC 892569 (3a), 892570 (3e) and 892571 (3i). Copies of the data can be obtained free of charge on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK [Fax: [phone]; E-mail: [e-mail]] or via www.ccdc.cam.ac.uk/data_request/cif. Compound 3a: C₃₀H₂₄N₂O; unit cell parameters: a = 10.2471(14) Å, b = 11.6921(11) Å, c = 19.105(3) Å, β = 99.605(11)°, space group P21/c. Compound 3e: C₃₀H₂₃BrN₂O; unit cell parameters: a = 6.6599(13) Å, b = 19.948(4) Å, c = 17.974(3) Å, β = 98.107(18)°, space group P21/n. Compound 3i: C₃₀H₂₂Cl₂N₂O; unit cell parameters: a = 8.3466(18) Å, b = 33.171(5) Å, c = 10.746(3) Å, β = 126.096(16)°, space group P21/c.