Synthesis 2014; 46(10): 1413-1420
DOI: 10.1055/s-0033-1340902
paper
© Georg Thieme Verlag Stuttgart · New York

Regioselective Synthesis of Dihydropyridocoumarin and Phenanthrolinone Derivatives­ via Iron(III) Chloride Mediated Intramolecular Cyclization

K. C. Majumdar*
Department of Chemistry, University of Kalyani, Kalyani 741235, West Bengal, India   Fax: +91(33)25828282   Email: kcmklyuniv@gmail.com
,
Sudipta Ponra
Department of Chemistry, University of Kalyani, Kalyani 741235, West Bengal, India   Fax: +91(33)25828282   Email: kcmklyuniv@gmail.com
› Author Affiliations
Further Information

Publication History

Received: 17 December 2013

Accepted after revision: 13 February 2014

Publication Date:
24 March 2014 (online)


Abstract

Potentially bioactive angular dihydropyridocoumarin and phenanthrolinone derivatives are synthesized in good to excellent yields using readily available iron(III) chloride (FeCl3) as the catalyst. The process is very simple, straightforward and inexpensive, and provides a diverse range of pyranoquinolone or phenan­throlinone derivatives, via a 6-endo-dig mode of cyclization, starting from simple and easily available 6-(N-propargyl)aminocoumarin and -quinolone derivatives.

Supporting Information

 
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