Planta Med 2013; 79 - PK13
DOI: 10.1055/s-0033-1348637

Secondary Metabolites from the Soft Coral Sinularia nanolobata

CY Duh 1, FY Hsu 1, SK Wang 2
  • 1Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan
  • 2Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan

Soft coral Sinularia nanolobata was reported to contain xeniaphyllane-type diterpenoids, caryophyllane-type norsesquiterpenoids, and furanone derivative. An investigation on the chemical constituents of the coral Sinularia nanolobata collected at San-Shen-Tai has led to the isolation of six new compounds (1-6), including two novel skeletons (1 and 2), two new diterpenoids (3 and 4), and two new norsesquiterpenes (5 and 6). The structures of these compounds were determined on the basis of their spectroscopic analysis (1H NMR, 13C NMR, 1H-1H COSY, HSQC, HMBC, IR and HRESIMS) and their cytotoxic and antiviral activities were evaluated.