Planta Med 2016; 82 - PC61
DOI: 10.1055/s-0036-1578763

Phytochemical Constituents Of Tinospora Sinensis

A Parveen 1, 2, Z Ali 2, O Fantoukh 1, 2, IA Khan 1, 2
  • 1Department of Biomolecular Sciences, Division of Pharmacognosy
  • 2National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA

Tinospora sinensis (Lour.) Merr. is a deciduous, climbing shrub producing stems up to 20 meters that twine around other plants for support [1]. The stems locally known as “Shen-Jin-Teng” are used in traditional medicine for the treatment of rheumatism, bruises and lumber muscle strain [2] in China. It is also used for the treatment of ulcerated wounds and to treat piles [3], fever, jaundice and burning sensation [4]. Phytochemical investigation of the stems of T. sinensis yielded cycloeucalenone (1), and cycloeucalenol (2) in addition to sterols, β-sitosterol and stigmasterol. Sugars and fatty acids constituted bulk of the extract. The structures of the compounds were elucidated by spectroscopic methods, including 1D and 2D NMR experiments and HRESIMS.

Fig. 1

Acknowledgements: This research is supported by “Science Based Authentication of Dietary Supplements” funded by the Food and Drug Administration grant number 1U01FD004246 – 05.

References: [1] Flora of China (1994) Missouri Botanical Garden Press; St. Louis. [2] Jiangsu New Medicinal College (1977) Dictionary of traditional Chinese medicine (p. 1393). [3] Li RW, Lin GD, et al. (2003) Anti-inflammatory activity of Chinese medicinal vine plants. J Ethnopharmacol; 85:61 – 6. [4] Pimpriker RB et al. (2009) Hypoglycemic Activity of T. sinensis (Linn) leaves. J Pharm Res.; 2:729 – 730.