CC BY ND NC 4.0 · SynOpen 2017; 01(01): 0015-0023
DOI: 10.1055/s-0036-1588809
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A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines

Nirnita Chakraborty Ghosal
Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India
,
Sachinta Mahato
Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India
,
Rana Chatterjee
Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India
,
Sougata Santra
Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University, 19 Mira Str., 620002 Yekaterinburg, Russian Federation
,
Grigory V. Zyryanov
Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University, 19 Mira Str., 620002 Yekaterinburg, Russian Federation
Institute of Organic Synthesis, Ural Division of the Russian Academy of Sciences, 22 S. Kovalevskoy Str., 620219 Yekaterinburg, Russian Federation   Email: adinath.majee@visva-bharati.ac.in
,
Adinath Majee*
Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India
› Author Affiliations
Further Information

Publication History

Received: 02 March 2017

Accepted after revision: 09 April 2017

Publication Date:
25 April 2017 (online)

Abstract

We have developed a new synthetic method for the synthesis of aziridines using Chloramine-T as an effective reagent in the presence of NH2OH·HCl and NaIO4. We found that the same combination of NH2OH·HCl and NaIO4 is also very effective for nucleophilic ring opening of aziridines.

 
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