CC BY ND NC 4.0 · SynOpen 2017; 01(01): 0050-0058
DOI: 10.1055/s-0036-1590800
Copyright with the author

Efficient Synthesis of Pyrazinoic Acid Hybrid Conjugates

Siva S. Panda*a, Abdullah M. Asirib, Mohamed Elagawanyc, Devan D. Buchanana, Behrad Torkiana, Keerthana Bathalaa, Sean J. Thomasa, Jason E. Capitoa, Muhammad N. Arshadb, Abeer N. Al-Romaizanb
  • aDepartment of Chemistry & Physics, Augusta University, Augusta, GA 30912, USA
  • bChemistry Department, Faculty of Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabia
  • cDepartment of Pharmaceutical Chemistry, faculty of pharmacy, Damanhour University, Damanhour, Egypt   Email:   Email:
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Publication History

Received: 05 April 2017

Accepted after revision: 31 May 2017

Publication Date:
06 July 2017 (online)


Benzotriazole-activated pyrazinoic acid was utilized as a versatile building block for the efficient and convenient synthesis of novel hybrid conjugates of pyrazinoic acid with secondary amines via amino acid linkers in high yields.

Supporting Information