Synlett 2018; 29(08): 1087-1091
DOI: 10.1055/s-0036-1591898
letter
© Georg Thieme Verlag Stuttgart · New York

An Efficient Microwave-Assisted Propylphosphonic Anhydride (T3P®)-Mediated One-Pot Chromone Synthesis via Enaminones

C. Balakrishna
a  Chemistry Services, GVK Biosciences Pvt. Ltd., Survey Nos:125 (part) & 126, IDA Mallapur, Hyderabad-500076, Telangana, India   Email: [email protected]
b  Department of Chemistry, GITAM University, Visakhapatnam, Rushikonda, Andhrapradesh State, 530045, India
,
Venu Kandula
a  Chemistry Services, GVK Biosciences Pvt. Ltd., Survey Nos:125 (part) & 126, IDA Mallapur, Hyderabad-500076, Telangana, India   Email: [email protected]
,
Ramakrishna Gudipati
a  Chemistry Services, GVK Biosciences Pvt. Ltd., Survey Nos:125 (part) & 126, IDA Mallapur, Hyderabad-500076, Telangana, India   Email: [email protected]
,
Satyanarayana Yennam
a  Chemistry Services, GVK Biosciences Pvt. Ltd., Survey Nos:125 (part) & 126, IDA Mallapur, Hyderabad-500076, Telangana, India   Email: [email protected]
,
P. Uma Devi
b  Department of Chemistry, GITAM University, Visakhapatnam, Rushikonda, Andhrapradesh State, 530045, India
,
Manoranjan Behera*
a  Chemistry Services, GVK Biosciences Pvt. Ltd., Survey Nos:125 (part) & 126, IDA Mallapur, Hyderabad-500076, Telangana, India   Email: [email protected]
› Author Affiliations
We are grateful to GVK Biosciences Pvt. Ltd., for financial support and encouragement.
Further Information

Publication History

Received: 16 November 2017

Accepted after revision: 26 December 2017

Publication Date:
29 January 2018 (online)


Abstract

An efficient synthesis of 4H-chromene-4-ones via enamino ketones, with cyclization by using T3P® under microwave heating is described. This is the first report for the synthesis of chromones by using T3P®. Significant features of this method include short reaction times and high-purity products.

Supporting Information

 
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