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Synthesis 2018; 50(17): 3499-3505
DOI: 10.1055/s-0037-1610168
DOI: 10.1055/s-0037-1610168
paper
Phosphine-Free [3+2] Cycloaddition of Propargylamines with Dialkyl Azodicarboxylates: An Efficient Access to Pyrazole Backbone
Authors
We gratefully acknowledge the National Natural Science Foundation of China (No. 21472121) for financial support.
Weitere Informationen
Publikationsverlauf
Received: 13. März 2018
Accepted after revision: 28. April 2018
Publikationsdatum:
18. Juni 2018 (online)
Abstract
A phosphine-free [3+2] cycloaddition reaction of the substituted propargylamines with dialkyl azodicarboxylates at room temperature is described. This reaction provides a new approach to functionalized pyrazoles in good yields and high selectivity.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1610168.
- Supporting Information (PDF)
-
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