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Synlett 2018; 29(18): 2381-2384
DOI: 10.1055/s-0037-1610632
letter
© Georg Thieme Verlag Stuttgart · New York

Two Propanediurea-based Cucurbituril Analogues: Bis-ns-TD[8] and NH-ns-TD[4]

Chunhua Dai
,
Yenan Shen
,
Qiaochun Wang  *
Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, P. R. of China   Email: qcwang@ecust.edu.cn
› Author AffiliationsThis work was financially supported by the NSFC/China (21572063 and 21372076), the Science Fund for Creative Research Groups (21421004), the Program of Introducing Talents of Discipline to Universities (B16017), and the Fundamental Research Funds for the Central Universities (222201717003).
Further Information

Publication History

Received: 13 June 2018

Accepted after revision: 09 August 2018

Publication Date:
31 August 2018 (online)

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Abstract

Two new cucurbituril members, one containing two equivalent cavities and the other having an active secondary amine group, were synthesized by condensation of propanediurea (2,4,6,8-tetraazabicyclo[3.3.1]nonane-3,7-dione) with formaldehyde. These two macrocycles exhibit excellent thermal stability, and their structures were confirmed by single-crystal X-ray diffraction, 1H NMR spectroscopy, and high-resolution mass spectrometry.

Key words

cucurbiturils - propanediurea - macrocycles - condensation - supramolecular chemistry

Supporting Information

    Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1610632.
  • Supporting Information

Primary Data

    for this article are available online at https://doi.org/10.1055/s-0037-1610632 and can be cited using the following DOI: 10.4125/pd0101th.
  • Primary Data
 

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