Synthesis 2019; 51(11): 2430-2434
DOI: 10.1055/s-0037-1612415
paper
© Georg Thieme Verlag Stuttgart · New York

Green Access to α-Haloalkyl and α-Halobenzyl Esters, Versatile Intermediates for the One-Pot Two-Step Synthesis of O,O′-Diacyl Acetals Using Zinc-Based Ionic Liquid Catalyst

Fabienne Fache*
a  Univ Lyon, Université Claude Bernard Lyon 1, CNRS, INSA Lyon, CPE Lyon, ICBMS, UMR 5246, 69622 Villeurbanne Cedex, France   Email: fabienne.fache@univ-lyon1.fr
,
Ignasi de Azpiazu
a  Univ Lyon, Université Claude Bernard Lyon 1, CNRS, INSA Lyon, CPE Lyon, ICBMS, UMR 5246, 69622 Villeurbanne Cedex, France   Email: fabienne.fache@univ-lyon1.fr
,
Béatrice Pelotier
a  Univ Lyon, Université Claude Bernard Lyon 1, CNRS, INSA Lyon, CPE Lyon, ICBMS, UMR 5246, 69622 Villeurbanne Cedex, France   Email: fabienne.fache@univ-lyon1.fr
,
a  Univ Lyon, Université Claude Bernard Lyon 1, CNRS, INSA Lyon, CPE Lyon, ICBMS, UMR 5246, 69622 Villeurbanne Cedex, France   Email: fabienne.fache@univ-lyon1.fr
,
Christel Gozzi
b  CPE-Lyon, Campus Lyon Tech-La Doua, 43 bd du 11 novembre 1918, 69616 Villeurbanne, France
› Author Affiliations
Financial support from Université Lyon 1 and CNRS are warmly acknowledged.
Further Information

Publication History

Received: 28 January 2019

Accepted after revision: 16 February 2019

Publication Date:
14 March 2019 (eFirst)

Abstract

α-Haloalkyl and α-halobenzyl esters have been synthesized using a zinc-based ionic liquid catalyst, BMIZnCl3. These esters can then react with acids without intermediate purification to obtain mixed O,O′-diacyl acetals in a one-pot process.

Supporting Information

 
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