Crystalloid Administration Is Associated with the Recovery of Pediatric Elective Roux-en-Y HepaticojejunostomyFunding This study was funded by grants from the National Natural Science Foundation of China (No: 30973440, 30770950) and the key project of the Chongqing Natural Science Foundation (CSTC, 2008BA0021, cstc2012jjA0155).
31. Juli 2018
13. Dezember 2018
21. Januar 2019 (online)
Background Intraoperative fluid administration is important for postoperative recovery and might be associated with postoperative complications.
Materials and Methods This retrospective review included 471 patients who underwent Roux-en-Y hepaticojejunostomy. Patients were separated into two groups based on whether they received low (<15.27 mL/kg/h) or high (>15.27 mL/kg/h) volumes of corrected crystalloid fluids. Propensity score matching was performed to adjust for any potential selection bios for the two groups. In 192 matched patients, clinical outcomes, including postoperative complications and length of hospital stay, were compared.
Results Higher use of diuresis (p = 0.027) was found in the high fluid group. Receiving low volumes of crystalloids was associated with postoperative gastrointestinal functional recovery, reflected by the first defecation (odds ratio [OR], 0.69; 95% confidence interval [CI], 0.31–1.07; p = 0.047) and first bowel movement (OR, 0.56; 95% CI, 0.38–0.98; p = 0.013). However, the occurrence of renal complications did not show significant differences between the groups. A lower postoperative complication rate (OR, 0.54; 95% CI, 0.42–0.94; p = 0.016) was noted in patients with low crystalloids compared with high crystalloids. The total length of hospital stay was longer in patients with high crystalloid fluid (9.21 ± 3.24 days) than patients with low volumes (7.83 ± 2.58 days; p = 0.012).
Conclusion Low crystalloid fluid administration was associated with favorable postoperative outcomes.
Keywordscrystalloid administration - length of hospital stay - abdominal surgery - acute kidney injury
Xingqin Tan designed and analyzed the data and evaluated the article. Jianxia Liu performed the statistical measurements and analyzed the data. Chunbao Guo analyzed the data and wrote the article.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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