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Synfacts 2020; 16(03): 0247
DOI: 10.1055/s-0039-1691691
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of a Macrocyclic Mcl-1 Inhibitor

Contributor(s):
Philip Kocienski
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Publication History

Publication Date:
18 February 2020 (online)

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Key words

Mcl-1 inhibitor - ring-closing metathesis - macrocyclization - Reformatsky reaction - α-hydroxy phenylacetic acids