Planta Medica, Table of Contents Planta Med 2019; 85(18): 1406DOI: 10.1055/s-0039-3399680 Abstracts of Plenary Lectures © Georg Thieme Verlag KG Stuttgart · New YorkEndocannabinoid signaling across species – evolution and perspectives for drug discovery J Gertsch 1 University of Bern, Institute of Biochemistry and Molecular Medicine, NCCR TransCure, Bühlstrasse 28, CH-3012 Bern, Switzerland› Author AffiliationsRecommend Article Abstract Full Text References References 1 Gachet MS, Schubert A, Calarco S, Boccard J, Gertsch J. Targeted metabolomics shows plasticity in the evolution of signaling lipids and uncovers old and new endocannabinoids in the plant kingdom. Sci Rep 2017; 7: 41177. 2 Chen AL, Lum KM, Lara-Gonzalez P, Ogasawara D, Petrascheck M, Bar-Peled L, Cravatt BF. Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. Nat Chem Biol 2019; 15: 453-462 3 Gertsch J. Scaffold and organism hopping with chemical probes. Nat Chem Biol 2019; 15: 428-429. 4 Chicca A, Schafroth MA, Reynoso-Moreno I, Erni R, Petrucci V, Carreira EM, Gertsch J. Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high. Sci Adv 2018; 4: eaat2166. 5 Gertsch J. Cannabimimetic phytochemicals in the diet - an evolutionary link to food selection and metabolic stress adaptation?. Br J Pharmacol 2017; June; 174 (11) 1464-1483.