Synthesis 2023; 55(02): 159-163
DOI: 10.1055/s-0040-1720037

Professor Alain Krief: Advancing Chemistry; From Innovative Synthesis to Promoting Sustainable Development

Henning Hopf
a   Institute of Organic Chemistry, Technische Universität Braun­schweig, Hagenring 30, D-38106 Braunschweig, Germany
b   School of Chemistry, University of Hyderabad, Prof. CR Rao Road, Gachibowli, Hyderabad 500046, India
c   Institute of Global Health Innovation, Imperial College London, Faculty Building, South Kensington, London SW7 2AZ, UK
› Author Affiliations

Dedicated to our dear friend, colleague and inspiration, Alain Krief, on his 80th birthday.


Over more than five decades, Alain Krief’s career has encompassed many contributions to chemistry, notably in his innovative work in the areas of organic synthesis and the use of inorganic and organic reagents, as well as his work on bioorganic chemistry and applications of information technology in chemistry. His research on the synthesis of cyclopropanes, including chrysanthemic acid and other pyrethroids, and the uses of selenium compounds in organic synthesis, have been of particular importance and have found widespread applications. In addition, his roles in international collaborations in research and his leadership of the International Organization for Chemical Sciences in Development from 2009 to 2020 have marked his strong commitment to the importance of chemistry as a science for the benefit of society and a contributor to the goal of sustainable development.

1 Introduction

2 A Spectrum of Research

3 Leadership of the International Organization for Chemical Sciences in Development (IOCD)

Publication History

Received: 03 August 2022

Accepted: 03 August 2022

Article published online:
12 December 2022

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  • References

    • 1a Prof. Alain Krief: Curriculum Vitae. International Center for Chemical and Biological Sciences, HEJ Research Institute for Chemical Sciences, University of Karachi, Pakistan, May 2019, see: (accessed Nov. 16, 2022).
    • 1b A Tribute to Prof. Alain Krief: Provins L. ARKIVOC 2007; (x): 1
    • 1c Bonifazi D, Ghosez L. Eur. J. Org. Chem. 2009; 1640
    • 1d Alain Krief: Profile, see: (accessed Nov. 16, 2022).
    • 2a Castillo-Colaux C, Krief A. Int. J. Knowl. Learn. 2008; 4: 152
    • 2b Krief A, Castillo-Colaux C, Henry J, Juilliard C, Peraldi S. Int. J. Knowl. Learn. 2008; 4: 203
    • 2c Sankar P, Krief A, Vijayasarathi D. J. Mol. Graphics Model. 2013; 43: 1
    • 2d Krief A. Chem. Rec. 2016; 16: 520
  • 3 Krief A, Dumont W, Pasau P. Tetrahedron Lett. 1988; 29: 1079
  • 4 Krief A, Lecomte P, Demoute JP, Dumont W. Synthesis 1990; 275
  • 6 Krief A. Selenium . In Comprehensive Organometallic Chemistry . Abel EW, Stone EG. A, Wilkinson G. Elsevier; Oxford: 1995: 515-569
  • 7 Krief A, Hevesi L. Organoselenium Chemistry I: Functional Group Transformations . Springer Science & Business Media; Berlin: 2011
  • 8 Krief A, Nazih A, Hobe M. Tetrahedron Lett. 1995; 36: 8111
  • 9 Matlin SA, Krief A. Chim. Nouv. 2018; 129: 1
  • 10 Seaborg GT. Science 1984; 223: 9
    • 11a O’Sullivan DA. Chem. Eng. News 1983; 61: 21
    • 11b Lehn J.-M, Blout ER, Maybury RH. Chem. Int. 2002; 24: 3
  • 12 Rosei F, Matlin SA. Chem. Int. 2021; 43: 11
  • 13 Hopf H, Krief A, Matlin SA, Mehta G. Chemists for Sustainability: Overview of Topics and Publications. International Organization forChemical Sciences in Development. Namur; Belgium: 2021. http// (accessed Nov. 16, 2022)
    • 14a Matlin SA, Mehta G, Hopf H, Krief A. Nat. Chem. 2015; 7: 941
    • 14b Matlin SA, Mehta G, Hopf H, Krief A. Nat. Chem. 2016; 8: 393
    • 15a Learning Objectives and Strategies for Infusing Systems Thinking into (Post)-Secondary General Chemistry Education. IUPAC Project 2017-010-1-050, see: (accessed Nov. 16, 2022).
    • 15b Systems Thinking in Chemistry for Sustainability: Toward 2030 and Beyond (STCS 2030+). IUPAC Project 2020-014-3-050, see: (accessed Nov. 16, 2022).
  • 16 Mahaffy PG, Matlin SA. Actual. Chim. 2019; 446: 47