Eur J Pediatr Surg
DOI: 10.1055/s-0041-1722904
Original Article

Congenital Heart Defects in Patients with Classic Bladder Exstrophy: A Hitherto Neglected Association?

Martin Promm
1  Department of Pediatric Urology, Clinic St. Hedwig, University Medical Center of Regensburg, Regensburg, Germany
,
Stephan Gerling
2  Department of Pediatrics, University Children's Hospital Regensburg (KUNO), Campus St. Hedwig, Regensburg, Germany
,
Carsten P. Schepp
3  Department of Anesthesiology and Pediatric Anesthesiology, Clinic St. Hedwig, Barmherzige Brüder Hospital Regensburg, Regensburg, Germany
,
Wolfgang H. Rösch
1  Department of Pediatric Urology, Clinic St. Hedwig, University Medical Center of Regensburg, Regensburg, Germany
› Author Affiliations

Abstract

Introduction Classic bladder exstrophy (BE) is regarded as an isolated malformation without any further anomalies, but some studies have indicated a higher incidence of cardiac anomalies. This cross-sectional study is planned to evaluate the prevalence of congenital heart defects (CHDs) and the clinical relevance for patients with BE admitted for primary closure.

Materials and Methods Patients were prospectively recruited between March 2012 and January 2019. Patients' profiles including demographic data, results of transthoracic echocardiography (TTE), as well as essential peri- and postoperative data were assessed.

Results Thirty-nine (25 boys and 14 girls) patients with BE (median age 61 days) underwent delayed primary bladder closure. Thirty-seven (24 boys and 13 girls) patients had received TTE 1 day before surgery. CHD was detected in 7 (18.9%) out of the 39 patients, but no clinical differences between patients with and without CHD were observed peri- or postoperatively.

Discussion and Conclusion This prospective systematic evaluation shows an even higher rate of CHD in patients with BE than assumed previously. Although peri- and postoperative outcome did not differ between patients with and without CHD, we consider TTE an important additional method for ensuring a safe peri- and postoperative courses and a short- and long-term care for patients with CHD.



Publication History

Received: 03 August 2020

Accepted: 14 December 2020

Publication Date:
07 March 2021 (online)

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