Planta Med 2016; 82(16): 1431-1437
DOI: 10.1055/s-0042-108339
Natural Product Chemistry and Analytical Studies
Original Papers
Georg Thieme Verlag KG Stuttgart · New York

Effect of Accessions and Environment Conditions on Coumarin, O-Coumaric and Kaurenoic Acids Levels of Mikania laevigata

Tânia da Silveira Agostini-Costa
1  Embrapa Recursos Genéticos e Biotecnologia, Brasília, DF, Brazil
,
Ismael Silva Gomes
1  Embrapa Recursos Genéticos e Biotecnologia, Brasília, DF, Brazil
,
Maira Christina Marques Fonseca
2  Empresa de Pesquisa Agropecuária de Minas Gerais – EPAMIG, Viçosa, MG, Brazil
,
Araci Molnar Alonso
3  Embrapa Cerrados, Planaltina, DF, Brazil
,
Rita de Cassia Alves Pereira
4  Embrapa Agroindústria Tropical, Fortaleza, CE, Brazil
,
Ilio Montanari Junior
5  Centro Pluridisciplinar de Pesquisas Químicas Biológicas e Agrícolas – CPQBA (UNICAMP), Campinas, SP, Brazil
,
Joseane Padilha da Silva
1  Embrapa Recursos Genéticos e Biotecnologia, Brasília, DF, Brazil
,
Ana Maria Soares Pereira
6  Universidade de Ribeirão Preto – UNAERP, Ribeirão Preto, SP, Brazil
,
Dijalma Barbosa da Silva
1  Embrapa Recursos Genéticos e Biotecnologia, Brasília, DF, Brazil
,
Roberto Fontes Vieira
1  Embrapa Recursos Genéticos e Biotecnologia, Brasília, DF, Brazil
,
Ana Paula Artimonte Vaz
7  Embrapa Produtos e Mercado, Campinas, SP, Brazil
› Author Affiliations
Further Information

Publication History

received 25 August 2015
revised 26 April 2016

accepted 30 April 2016

Publication Date:
23 June 2016 (online)

Abstract

Coumarin, o-coumaric, and kaurenoic acid are bioactive compounds usually found in the leaves of Mikania laevigata. Genetic and environmental variations in the secondary metabolites of plants may have implications for their biological effects. Three different accessions of M. laevigata cultivated in four sites between the Equator and the Tropic of Capricorn in Brazil were evaluated aiming to present potential raw materials and discuss relationships among these three bioactive compounds. The results revealed effects of plant accessions and environmental factors and suggested two contrasting chemical phenotypes of M. laevigata. The first phenotype presented the highest levels of kaurenoic acid (2283 ± 316 mg/100 g) besides lower levels of coumarin (716 ± 61 mg/100 g), which was also stimulated by the environment and mild climate at the site nearest to the Tropic of Capricorn. The other phenotype presented the lowest levels of kaurenoic acid (137 ± 17 mg/100 g) besides higher levels of coumarin (1362 ± 108 mg/100 g), which was also stimulated by the environment and tropical climate at the site nearest to the Equatorial beach.

Supporting Information