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DOI: 10.1055/s-0042-1759291
New Hops-Products for Neuroprotection and Regeneration: Consumer Insights and Product Expectations
Innovative Natural Health Products (NHP) – including herbal medicinal products as well as natural food supplements – show growing demand in Germany. In recent years researchers scrutineered by-products of the hops processing industry and found secondary plant compounds (prenyl flavonoids) having the potential to stimulate the formation of neurons [1], [2], [3]. These herbal extracts have the potential to extend the use of hops (Humulus lupulus L.) as a medicinal plant from sleep aids to modern therapeutic approaches in the fields of neurodegenerative diseases (e.g., dementia, depression) and neuroprotection (e.g., cognition enhancers).
To address the potential target group of these new application fields a deeper understanding of consumer demand and the reasons, leading to the choice of new NHPs, is essential. Therefore, a national representative online survey with 1.707 participants was carried out in Germany in April 2022. The survey queried the general use of NHPs in Germany and the interest for an innovative cognition enhancer based on hops. Product attributes that attract potential consumers to such a product, was determined with a choice experiment. All these analyses will contribute to assess the therapeutic demand and to define a target group for new neuroactive hop-NHPs.
There are no conflicts of interest.
Publication History
Article published online:
12 December 2022
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References
- 1 Oberbauer E, Urmann C, Steffenhagen C. et al. Chroman-like cyclic prenylflavonoids promote neuronal differentiation and neurite outgrowth and are neuroprotective. The Journal of nutritional biochemistry 2013; 24: 1953-1962
- 2 Urmann C, Oberbauer E, Couillard-Després S. et al. Neurodifferentiating potential of 8-prenylnaringenin and related compounds in neural precursor cells and correlation with estrogen-like activity. Planta Med 2015; 81: 305-311
- 3 Kirchinger M, Bieler L, Tevini J. et al. Development and characterization of the neuroregenerative xanthohumol c/Hydroxypropyl-β-cyclodextrin complex suitable for parenteral administration. Planta medica 2019; 85: 1233-1241