Download PDF
Synthesis 1985; 1985(10): 953-955
DOI: 10.1055/s-1985-31399
communication
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Nicotine Chemistry. The Addition of Alkyl Radicals to (S)-(-)-Nicotine: Synthesis of Optically Active 6-Alkylnicotines

Jeffrey I. Seeman* , Leigh E. Clawson, Henry V. Secor
  • *Philip Morris U.S.A. Research Center, P.O. Box 26583, Richmond, Virginia 23261, U.S.A.
Further Information

Publication History

Publication Date:
27 September 2002 (online)

 PDF Download  Permissions and Reprints All articles of this category
Preview

Radical alkylation of (S)-nicotine (1) with alkanoic acids (6) in the presence of ammonium peroxydisulfate and silver nitrate to give optically active 6-alkylnicotines 4 is described.