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Synthesis 1989; 1989(12): 949-950
DOI: 10.1055/s-1989-27441
DOI: 10.1055/s-1989-27441
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data processing and storage.Efficient Conversion of Nitriles to Amides with Basic Hydrogen Peroxide in Dimethyl Sulfoxide
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Publikationsdatum:
02. Mai 2002 (online)
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Nitriles 1 are efficiently transformed into N-unsubstituted amides 2 at 20°C in 5-30 mins in good yield and with high selectivity, using basic 30% hydrogen peroxide in dimethyl sulfoxide.