Synthesis 1990; 1990(1): 84-86
DOI: 10.1055/s-1990-26796
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Synthesis of Ethyl 5-Aryl-2-oxo-7-phenyl-1,2,3,4,4a,5-hexahydroquinoline-4a-carboxylates

K. Popandova-Yambolieva*
  • *Department of Chemistry, University of Sofia, BG-1126 Sofia, Bulgaria
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Publikationsverlauf

Publikationsdatum:
17. September 2002 (online)

The addition of ethyl 6-aryl-4-phenyl-2-oxo-3-cyclohexene-1-carboxylates 1a-e to acrylonitrile in the presence of aqueous sodium hydroxide is studied. The products 2a-e are transformed to the corresponding 2-oxo-1,2,3,4,4a,5-hexahydroquinolines 3 by heating with ammonium acetate at 180°C.

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